Research

RESEARCH - CLINICAL TRIALS

Healthcare Innovations Institute

Our research mission at the Healthcare Innovations Institute, an affiliate of The Neurology Institute, is to provide state of the art medical care and opportunities for patients to participate in clinical trials. Here our physicians are educated and informed on new drugs and devices, from pharmaceuticals to biotechnology, to use better strategies with our medical treatments for patients. In addition, our multi-lingual staff are able to explain the clinical trials thoroughly to our patients and answer any questions they may have.

Our physicians and nurse practitioners involved with research are on staff at Broward Health North, Coral Springs Medical Center, North West Medical Center, University Hospital and Kindred Hospital Hollywood and Fort Lauderdale. Daily, we have been successful in enrolling for all clinical trials offered.

Our facility includes: - Exam Rooms

- IV Infusion Services - Wifi Web - Ex & Video Conferences - Off Site Temperature Storage Facility

- Designated Laboratory & Centrifuges - Temperature Controlled Drug Freezer ( -20 °C ) & Refrigerators (2-8 °C) - Double Locked Medication Room- Dry Ice

Accessibility: - Free Parking / Transit Bus Line - Senior Shuttle Stops in front of the building - Miami & Fort Lauderdale International Airports

- Emergency Room 200 Ft from the Research Facility with 911 Paramedics.

CALL (954) 530-5844 FOR MORE INFORMATION

Parkinson's Disease

We are proud to offer patients ground breaking therapeutic options at multiple stages of the disease. We are actively enrolling patients in Phase II, Phase III and Phase IV clinical trials for Parkinson's Disease. This provides us revolutionary alternatives to conventional regimens.

Multiple Sclerosis (MS)

We participate in several clinical trials for MS. We understand this diseases multiple forms and presentations. We continue to pursue additional clinical trials to offer promising results. We also have a non-interventional trial involved with gathering data to better characterize the natural history of MS and to evaluate the effectiveness and safety of treatment medications for MS.

Traumatic Brain Injury (TBI)

At this time, we are able to provide cutting edge treatment options for patients suffering from traumatic brain injuries. We are actively enrolling patients in a clinical trial investigating the efficacy of a medication to treat neurobehavioral disinhibition (including aggression, agitation, and irritability) in patients with traumatic brain injury. We provide support with both neuropsychological testing and cognitive behavioral therapy.

Trigeminal Neuralgia

For patients suffering from this debilitating disorder, not only are we providing expertise with traditional medications, we are excited to offer a clinical trial evaluating the efficacy of a medication to treat patients with Trigeminal Neuralgia.

Alzheimer's Disease

As we continue to serve a large patient population with this progressive neurodegenerative disorder, with the support of clinical neuropsychologists and clinical psychologists, we understand the need for cutting edge research to combat this disease. We offer multiple clinical trials for Alzheimer's Disease. This includes ICARE AD Research Project. We are also excited to offer patients the opportunity to enroll in trial addressing Dementia with agitation. As medical providers we continue to acknowledge the need to minimize the caregiver burden.

Mood Disorders/Depression

Offering Pilot Study with supervised home based transcranial direct current stimulation for major depressive disorders (MDD). Enrolling for other mood disorders with a variety of therapeutic options.

CIDP (Chronic Inflammatory Demyelinating Polyneuropathy)

Introducing

Phase 2 Trial to Investigate the Efficacy, Safety, and Tolerability of Subcutaneously Administered Efgartigimod with rHuPH20 in Adult Patients with Chronic Inflammatory Demyelinating Polyneuropathy

Cancer

Investigating and analyzing cancer genetics for strategic targeting of genes and optimal Cancer Prevention.

Other Specialty Trials

Our site is also conducting several multiple specialty trials investigating interventional medication for a variety of neurological disorders.

Myasthenia Gravis

Now open for enrollment in

Phase 3B, Randomized, Open-label, Parallel-Group Trial to Evaluate Different Dosing Regimens of Intravenous Efgartigimod to Maximize and Maintain Clinical Benefit in Patients With Generalized Myasthenia Gravis

Alzheimer's Dementia

If you are a caregiver for someone with Alzheimer’s dementia, you may be familiar with the agitated behaviors that many people with this condition experience.

Examples of some easily identifiable agitated behaviors are:

• Restlessness

• Pacing/aimless wandering

• Screaming

• Kicking

• Shouting

• Hitting others or self

• Throwing things

• Pushing people

• Resistiveness

• Hurting self or others

• Constant unwarranted requests for attention or help

• Tearing things or destroying property

To be eligible for this study, a potential participant must:

Be between the ages of 50 and 90

Have a diagnosis of probable Alzheimer’s disease

Have moderate-to-severe agitation that interferes with their daily life

Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

WHO IS ELIGIBLE TO PARTICIPATE?

These are some of the requirements to participate in the study:

• Be at least 18 years old

• Be diagnosed with probable or definite CIDP, your study physician will determine this diagnosis

• Not be pregnant or nursing

• Be willing to travel to the study location on a regular basis

• Meet other criteria that the study staff will discuss

Multiple Sclerosis; Primary Progressive

• To be eligible for this study, you must:

• Be between 18 and 65 years old

• Be diagnosed with PPMS or SPMS

• Have not experienced worsening of MS symptoms within the past 2 years

This is a partial list of study requirements. The study doctor will review the full requirements for this study with you.

Multiple Sclerosis; Relapsing (RMS)

Study Period:

The trial consists of screening, a double-blind treatment period up to a maximum of 72 weeks, or shorter if certain MS-related activity occurs.

• You may be eligible to participate in the ENSURE study if you:

• Are between 18 and 55 years old

• Are diagnosed with RMS

• Have a recent history of active disease, meaning at least 2 relapses in the last 2 years or 1 relapse in the last year

CONTACT US TO LEARN MORE!

Better yet, see us in person! Contact us!

Come to our Coral Springs or Tamarac locationsHealthcare Innovations Institute THE NEUROLOGY INSTITUTE 5441 N UNIVERSITY DRIVE, SUITE 101

Coral Springs, FL 33067

RESEARCH@NEUROFL.COM(954) 530-5844

The Neurology Institute

✆ Phone (appointments): 954-803-9002

Address: 5441 N University Drive, Suite 101, Coral Springs, FL 33067

4.74